The Toxic Effects of Polychemotherapy onto the Liver Are Accelerated by the Upregulated MDR of Lymphosarcoma

Antitumor therapy of hematological malignancies is impeded due to the high toxicity of polychemotherapy toward liver and increasing multiple drug resistance (MDR) of tumor cells under the pressure of polychemotherapy. These two problems can augment each other and significantly reduce the efficiency...

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Main Authors: Sen'kova, Alexandra V., Mironova, Nadezhda L., Patutina, Olga A., Ageeva, Tatyana A., Zenkova, Marina A.
Format: Artigo
Jezik:Inglês
Izdano: International Scholarly Research Network 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517856/
https://ncbi.nlm.nih.gov/pubmed/23251817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/721612
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