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Tricks in Plasmodium’s molecular repertoire - escaping 3′UTR excision-based conditional silencing of the chloroquine resistance transporter locus

In the human malaria parasite, Plasmodium falciparum, the major determinant of chloroquine resistance, P. falciparum chloroquine resistance transporter (pfcrt), likely plays an essential role in asexual blood stages, thus precluding conventional gene targeting approaches. We attempted to conditional...

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Detalhes bibliográficos
Main Authors: Ecker, Andrea, Lewis, Rebecca E., Ekland, Eric H., Jayabalasingham, Bamini, Fidock, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517811/
https://ncbi.nlm.nih.gov/pubmed/23023047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2012.09.003
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