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Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer

BACKGROUND: Cancer is an extremely heterogeneous group of diseases traditionally categorized according to tissue of origin. However, even among patients with the same cancer subtype the cellular alterations at the molecular level are often very different. Several new therapies targeting specific mol...

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Autores principales: Kristensen, Lasse Sommer, Kjeldsen, Tina Ellegaard, Hager, Henrik, Hansen, Lise Lotte
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517778/
https://ncbi.nlm.nih.gov/pubmed/23173730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-548
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