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Competitive amplification of differentially melting amplicons (CADMA) improves KRAS hotspot mutation testing in colorectal cancer

BACKGROUND: Cancer is an extremely heterogeneous group of diseases traditionally categorized according to tissue of origin. However, even among patients with the same cancer subtype the cellular alterations at the molecular level are often very different. Several new therapies targeting specific mol...

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Autori principali: Kristensen, Lasse Sommer, Kjeldsen, Tina Ellegaard, Hager, Henrik, Hansen, Lise Lotte
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517778/
https://ncbi.nlm.nih.gov/pubmed/23173730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-548
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