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An improved strategy for the synthesis of [(18)F]-labeled arabinofuranosyl nuclosides

The expression of the herpes simplex virus type-1 thymidine kinase (HSV1-tk) gene can be imaged efficaciously using a variety of 2′-[(18)F]fluoro-2′-deoxy-1-b-D-arabinofuranosyl-uracil derivatives [[(18)F]-FXAU, X= I(iodo), E(ethyl), and M(methyl)]. However, the application of these derivatives in c...

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Autores principales: Zhang, Hanwen, Cantorias, Melchor V., Pillarsetty, NagaVaraKishore, Burnazi, Eva M., Cai, Shangde, Lewis, Jason S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517724/
https://ncbi.nlm.nih.gov/pubmed/22819195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.06.008
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