Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia

Prostaglandin E(2) (PGE(2)) contributes to cystogenesis in genetically nonorthologous models of autosomal dominant polycystic kidney disease (ADPKD). However, it remains unknown whether PGE(2) induces the classic features of cystic epithelia in genetically orthologous models of ADPKD. We hypothesize...

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Detalhes bibliográficos
Main Authors: Liu, Yu, Rajagopal, Madhumitha, Lee, Kim, Battini, Lorenzo, Flores, Daniel, Gusella, G. Luca, Pao, Alan C., Rohatgi, Rajeev
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517629/
https://ncbi.nlm.nih.gov/pubmed/22933297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00010.2012
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