Drug Cocktail Optimization in Chemotherapy of Cancer

BACKGROUND: In general, drug metabolism has to be considered to avoid adverse effects and ineffective therapy. In particular, chemotherapeutic drug cocktails strain drug metabolizing enzymes especially the cytochrome P450 family (CYP). Furthermore, a number of important chemotherapeutic drugs such a...

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Autores principales: Preissner, Saskia, Dunkel, Mathias, Hoffmann, Michael F., Preissner, Sarah C., Genov, Nikolai, Rong, Wen Wei, Preissner, Robert, Seeger, Karlheinz
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517625/
https://ncbi.nlm.nih.gov/pubmed/23236419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051020
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