Proteomic Investigations of Lysine Acetylation Identify Diverse Substrates of Mitochondrial Deacetylase Sirt3

Lysine acetylation is a posttranslational modification that is dynamically regulated by the activity of acetyltransferases and deacetylases. The human and mouse genomes encode 18 different lysine deacetylases (KDACs) which are key regulators of many cellular processes. Identifying substrates of KDAC...

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Bibliografiske detaljer
Main Authors: Sol, Eri Maria, Wagner, Sebastian A., Weinert, Brian T., Kumar, Amit, Kim, Hyun-Seok, Deng, Chu-Xia, Choudhary, Chunaram
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517600/
https://ncbi.nlm.nih.gov/pubmed/23236377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050545
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