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Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions

BACKGROUND: The nuclear receptors (NRs) are an important class of transcription factors that are conserved across animal phyla. Canonical NRs consist of a DNA-binding domain (DBD) and ligand-binding domain (LBD). While most animals have 20–40 NRs, nematodes of the genus Caenorhabditis have experienc...

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Detalhes bibliográficos
Main Authors: Weber, Katherine P, Alvaro, Christopher G, Baer, G Michael, Reinert, Kristy, Cheng, Genevieve, Clever, Sheila, Wightman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517510/
https://ncbi.nlm.nih.gov/pubmed/22690911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-12-81
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