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Involvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo

BACKGROUND: Glioblastoma is the most common and most aggressive form of malignant glioma and is very difficult to treat. Controlling tumour cell invasion and angiogenesis is essential to improve the prognosis of glioblastoma patients. Since constitutive activation of nuclear factor-κB (NF-κB) is nec...

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Detalhes bibliográficos
Main Authors: Nakabayashi, Hiromichi, Shimizu, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517477/
https://ncbi.nlm.nih.gov/pubmed/23039130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-453
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