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Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

OBJECTIVE: The aim of this study was to investigate whether evodiamine (EVO) could potentiate the antitumor activity of gemcitabine (GEM) in tongue cancer cells and determine its potential underlying mechanisms. MATERIALS AND METHODS: Human Tca8113 and CAL-27 tongue squamous carcinoma cell lines wer...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Guo, Qi, Liu, Yanmei, Zhao, Jiayuan, Wang, Jing, Li, Yue, Pang, Yunqing, Chen, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312051/
https://ncbi.nlm.nih.gov/pubmed/30643424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S181062
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