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Evodiamine inactivates NF-κB and potentiates the antitumor effects of gemcitabine on tongue cancer both in vitro and in vivo

OBJECTIVE: The aim of this study was to investigate whether evodiamine (EVO) could potentiate the antitumor activity of gemcitabine (GEM) in tongue cancer cells and determine its potential underlying mechanisms. MATERIALS AND METHODS: Human Tca8113 and CAL-27 tongue squamous carcinoma cell lines wer...

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Dettagli Bibliografici
Pubblicato in:Onco Targets Ther
Autori principali: Guo, Qi, Liu, Yanmei, Zhao, Jiayuan, Wang, Jing, Li, Yue, Pang, Yunqing, Chen, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312051/
https://ncbi.nlm.nih.gov/pubmed/30643424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S181062
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