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Mice Deficient in Urokinase-Type Plasminogen Activator Have Delayed Healing of Tympanic Membrane Perforations

Mice deficient in plasminogen, the precursor of plasmin, show completely arrested healing of tympanic membrane (TM) perforations, indicating that plasmin plays an essential role in TM healing. The activation of plasminogen to plasmin is performed by two plasminogen activators (PAs), urokinase-type P...

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Hlavní autoři: Shen, Yue, Guo, Yongzhi, Du, Chun, Wilczynska, Malgorzata, Hellström, Sten, Ny, Tor
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517469/
https://ncbi.nlm.nih.gov/pubmed/23236466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051303
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