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Mice Deficient in Urokinase-Type Plasminogen Activator Have Delayed Healing of Tympanic Membrane Perforations

Mice deficient in plasminogen, the precursor of plasmin, show completely arrested healing of tympanic membrane (TM) perforations, indicating that plasmin plays an essential role in TM healing. The activation of plasminogen to plasmin is performed by two plasminogen activators (PAs), urokinase-type P...

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Autores principales: Shen, Yue, Guo, Yongzhi, Du, Chun, Wilczynska, Malgorzata, Hellström, Sten, Ny, Tor
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517469/
https://ncbi.nlm.nih.gov/pubmed/23236466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051303
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