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Adipocyte Deficiency of Angiotensinogen Prevents Obesity-Induced Hypertension in Male Mice

Previous studies demonstrated that diet-induced obesity increased plasma angiotensin II concentrations and elevated systolic blood pressures in male mice. Adipocytes express angiotensinogen and secrete angiotensin peptides. We hypothesize that adipocyte-derived angiotensin II mediates obesity-induce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yiannikouris, Frederique, Gupte, Manisha, Putnam, Kelly, Thatcher, Sean, Charnigo, Richard, Rateri, Debra L., Daugherty, Alan, Cassis, Lisa A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517298/
https://ncbi.nlm.nih.gov/pubmed/23108647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.192690
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