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The eccentric cleavage product of β-carotene, β-apo-13-carotenone, functions as an antagonist of RXRα
In this study, we investigated the effects of eccentric cleavage products of β-carotene, i.e. β-apocarotenoids (BACs), on retinoid X receptor alpha (RXRα) signaling. Transactivation assays were performed to test whether BACs activate or antagonize RXRα. Reporter gene constructs (RXRE-Luc, pRL-tk) an...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517194/ https://ncbi.nlm.nih.gov/pubmed/20678466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.07.025 |
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