High-Sensitivity TFA-free LC-MS for Profiling Histones

The analysis of proteins by reversed-phase liquid chromatography (RPLC) commonly involves the use of TFA as an ion-pairing agent, even though it forms adducts and suppresses sensitivity. The presence of adducts can complicate protein molecular weight assignment especially when protein isoforms coelu...

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Autors principals: You, Jia, Wang, Liwen, Saji, Motoyasu, Olesik, Susan V., Ringel, Matthew D., Lucas, David M., Byrd, John C., Freitas, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517135/
https://ncbi.nlm.nih.gov/pubmed/21751347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201000445
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