Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response

ER stress leads to upregulation of multiple folding and quality control components, known as the unfolded protein response (UPR). Glucose Regulated Protein 78 (GRP78) (also known as binding immunoglobulin protein, BiP, and HSPA5) and GRP94 are often upregulated coordinately as part of this homeostat...

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Bibliographic Details
Main Authors: Eletto, Davide, Maganty, Avinash, Eletto, Daniela, Dersh, Devin, Makarewich, Catherine, Biswas, Chhanda, Paton, James C., Paton, Adrienne W., Doroudgar, Shirin, Glembotski, Christopher C., Argon, Yair
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517095/
https://ncbi.nlm.nih.gov/pubmed/22854046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.108928
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