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The use of integrase inhibitors in treatment-experienced patients

Raltegravir, the first approved HIV-1 integrase inhibitor, is able to block the strand transfer step of the HIV proviral DNA integration process into the cellular host DNA. The selected dosage for the pivotal phase III studies (subsequently approved by the regulatory agencies) was 400 mg bid by oral...

詳細記述

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書誌詳細
第一著者: Gatell, Jose M
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516826/
https://ncbi.nlm.nih.gov/pubmed/19959414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-14-S3-30
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