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Emerging role of integrase inhibitors in the management of treatment-experienced patients with HIV infection

Integrase is an essential HIV-1-specific enzyme that is an active target for antiretroviral drug development. Recently, a new class of drugs that specifically inhibits strand transfer, one of the three steps of HIV integration into the host DNA, has been developed. Two drugs in this class have reach...

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Bibliografiska uppgifter
Huvudupphovsmän: Katlama, Christine, Murphy, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697544/
https://ncbi.nlm.nih.gov/pubmed/19536321
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