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The use of integrase inhibitors in treatment-experienced patients

Raltegravir, the first approved HIV-1 integrase inhibitor, is able to block the strand transfer step of the HIV proviral DNA integration process into the cellular host DNA. The selected dosage for the pivotal phase III studies (subsequently approved by the regulatory agencies) was 400 mg bid by oral...

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Detalhes bibliográficos
Autor principal: Gatell, Jose M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516826/
https://ncbi.nlm.nih.gov/pubmed/19959414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-783X-14-S3-30
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