CDK5 Regulatory Subunit-associated Protein 1-Like 1 (CDKAL1) Is a Tail-anchored Protein in the Endoplasmic Reticulum (ER) of Insulinoma Cells

Genome-wide association studies have led to the identification of numerous susceptibility genes for type 2 diabetes. Among them is Cdkal1, which is associated with reduced β-cell function and insulin release. Recently, CDKAL1 has been shown to be a methylthiotransferase that modifies tRNA(Lys) to en...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brambillasca, Silvia, Altkrueger, Anke, Colombo, Sara Francesca, Friederich, Anne, Eickelmann, Peter, Mark, Michael, Borgese, Nica, Solimena, Michele
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516729/
https://ncbi.nlm.nih.gov/pubmed/23048041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.376558
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