Wird geladen...
NAD(P)H:quinone Oxidoreductase 1 (NQO1) Competes with 20S Proteasome for Binding with C/EBPα Leading to Its Stabilization and Protection against Radiation-induced Myeloproliferative Disease
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that protects cells against radiation and chemical-induced oxidative stress. Disruption of NQO1 gene in mice leads to increased susceptibility to myeloproliferative disease. In this report, we demonstrate that NQO1 controls the stability of m...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2012
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516712/ https://ncbi.nlm.nih.gov/pubmed/23086932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387738 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|