Analysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality

BACKGROUND: It has been a challenge to determine breast cancer clonality accurately. The aim of the present study was to assess methods using formalin-fixed paraffin-embedded (FFPE) tissue to differentiate new primary tumours from true recurrences that are associated with poorer prognoses and often...

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Detalhes bibliográficos
Main Authors: Masuda, S, Kadowaki, T, Kumaki, N, Tang, X, Tokuda, Y, Yoshimura, S, Takekoshi, S, Osamura, R Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516690/
https://ncbi.nlm.nih.gov/pubmed/23169290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.505
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