The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus

Viral attachment to target cells is the first step in infection and also serves as a determinant of tropism. Like many viruses, mammalian reoviruses bind with low affinity to cell-surface carbohydrate receptors to initiate the infectious process. Reoviruses disseminate with serotype-specific tropism...

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Bibliographische Detailangaben
Hauptverfasser: Reiss, Kerstin, Stencel, Jennifer E., Liu, Yan, Blaum, Bärbel S., Reiter, Dirk M., Feizi, Ten, Dermody, Terence S., Stehle, Thilo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516570/
https://ncbi.nlm.nih.gov/pubmed/23236285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003078
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