The Initial Draining Lymph Node Primes the Bulk of the CD8 T Cell Response and Influences Memory T Cell Trafficking after a Systemic Viral Infection

Lymphocytic choriomeningitis virus (LCMV) causes a systemic infection in mice with virus replication occurring in both peripheral tissues and secondary lymphoid organs. Because of the rapid systemic dissemination of the virus, the secondary lymphoid organs responsible for the induction of the LCMV-s...

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Bibliographic Details
Main Authors: Olson, Matthew R., McDermott, Daniel S., Varga, Steven M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516554/
https://ncbi.nlm.nih.gov/pubmed/23236277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003054
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