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Genomic Hallmarks of Genes Involved in Chromosomal Translocations in Hematological Cancer

Reciprocal chromosomal translocations (RCTs) leading to the formation of fusion genes are important drivers of hematological cancers. Although the general requirements for breakage and fusion are fairly well understood, quantitative support for a general mechanism of RCT formation is still lacking....

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Библиографические подробности
Главные авторы: Shugay, Mikhail, Ortiz de Mendíbil, Iñigo, Vizmanos, José L., Novo, Francisco J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516532/
https://ncbi.nlm.nih.gov/pubmed/23236267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002797
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