True 3q Chromosomal Amplification in Squamous Cell Lung Carcinoma by FISH and aCGH Molecular Analysis: Impact on Targeted Drugs

Squamous lung carcinoma lacks specific “ad hoc” therapies. Amplification of chromosome 3q is the most common genomic aberration and this region harbours genes having role as novel targets for therapeutics. There is no standard definition on how to score and report 3q amplification. False versus true...

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Detalhes bibliográficos
Main Authors: Brunelli, Matteo, Bria, Emilio, Nottegar, Alessia, Cingarlini, Sara, Simionato, Francesca, Caliò, Anna, Eccher, Albino, Parolini, Claudia, Iannucci, Antonio, Gilioli, Eliana, Pedron, Serena, Massari, Francesco, Tortora, Giampaolo, Borze, Ioana, Knuutila, Sakari, Gobbo, Stefano, Santo, Antonio, Tondulli, Luca, Calabrò, Francesco, Martignoni, Guido, Chilosi, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516520/
https://ncbi.nlm.nih.gov/pubmed/23236352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049689
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