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Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition

Heightened interest in relevant models for human disease increases the need for improved methods for germline transgenesis. We describe a significant improvement in the creation of transgenic laboratory mice and rats by chemical modification of Sleeping Beauty transposons. Germline transgenesis in m...

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Bibliografische gegevens
Hoofdauteurs: Carlson, Daniel F., Geurts, Aron M., Garbe, John R., Park, Chang-Won, Rangel-Filho, Artur, O'Grady, Scott M., Jacob, Howard J., Steer, Clifford J., Largaespada, David A., Fahrenkrug, Scott C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516389/
https://ncbi.nlm.nih.gov/pubmed/20352328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-010-9386-5
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