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Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression

Adaptation to hypoxia involves hypoxia-inducible transcription factors (HIFs) and requires reprogramming of cellular metabolism that is essential during both physiological and pathological processes. In contrast to the established role of HIF-1 in glucose metabolism, the involvement of HIFs and the...

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Hlavní autoři: Mylonis, Ilias, Sembongi, Hiroshi, Befani, Christina, Liakos, Panagiotis, Siniossoglou, Symeon, Simos, George
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516382/
https://ncbi.nlm.nih.gov/pubmed/22467849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.106682
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