Testing of Novel Dengue Virus 2 Vaccines in African Green Monkeys: Safety, Immunogenicity, and Efficacy

The immunogenicity and safety of three novel host-range vaccines containing deletions in the transmembrane domain of dengue virus serotype 2 (DV2) E glycoprotein were evaluated in African green monkeys. The shorter transmembrane domains are capable of functionally spanning an insect but not a mammal...

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Detalhes bibliográficos
Main Authors: Smith, Katherine M., Nanda, Kavita, McCarl, Victoria, Spears, Carla J., Piper, Amanda, Ribeiro, Mariana, Quiles, Michelle, Briggs, Caitlin M., Thomas, Gwynneth S., Thomas, Malcolm E., Brown, Dennis T., Hernandez, Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516330/
https://ncbi.nlm.nih.gov/pubmed/22890035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2012.12-0004
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