Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1

Autosomal-dominant polycystic kidney disease (ADPKD) and von Hippel-Lindau (VHL) disease lead to large kidney cysts that share pathogenetic features. The polycystin-1 (PC1) and pVHL proteins may therefore participate in the same key signaling pathways. Jade-1 is a pro-apoptotic and growth suppressiv...

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Bibliografiske detaljer
Main Authors: Foy, Rebecca L., Chitalia, Vipul C., Panchenko, Maria V., Zeng, Liling, Lopez, Delia, Lee, Jean W., Rana, Shaunak V., Boletta, Alessandra, Qian, Feng, Tsiokas, Leonidas, Piontek, Klaus B., Germino, Gregory G., Zhou, Mina I., Cohen, Herbert T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516131/
https://ncbi.nlm.nih.gov/pubmed/23001567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds391
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