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Morphine Epigenomically Regulates Behavior through Alterations in Histone H3 Lysine 9 Dimethylation in the Nucleus Accumbens

Dysregulation of histone modifying enzymes has been associated with numerous psychiatric disorders. Alterations in G9a (Ehmt2), a histone methyltransferase that catalyzes the euchromatic dimethylation of histone H3 at lysine 9 (H3K9me2), has been implicated recently in mediating neural and behaviora...

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Autors principals: Sun, HaoSheng, Maze, Ian, Dietz, David M., Scobie, Kimberly N., Kennedy, Pamela J., Damez-Werno, Diane, Neve, Rachael L., Zachariou, Venetia, Shen, Li, Nestler, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516048/
https://ncbi.nlm.nih.gov/pubmed/23197736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1357-12.2012
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