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Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain

Proper development of axonal connections is essential for brain function. A forward genetic screen for mice with defects in thalamocortical development previously isolated a mutant called baffled. Here we describe the axonal defects of baffled in further detail and identify a point mutation in the H...

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Detalhes bibliográficos
Main Authors: Favero, Carlita B., Henshaw, Rasha N., Grimsley-Myers, Cynthia M., Shrestha, Ayushma, Beier, David R., Dwyer, Noelle D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515720/
https://ncbi.nlm.nih.gov/pubmed/22821687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23199
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