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Recombination mapping using Boolean logic and high-density SNP genotyping for exome sequence filtering
Whole genome sequence data for small pedigrees has been shown to provide sufficient information to resolve detailed haplotypes in small pedigrees. Using such information, recombinations can be mapped onto chromosomes, compared with the segregation of a disease of interest and used to filter genome s...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3515651/ https://ncbi.nlm.nih.gov/pubmed/22264778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.12.014 |
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