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Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection

One of the major challenges in the development of targeted nanoparticles (NPs) for cancer therapy is to discover targeting ligands that allow for differential binding and uptake by the target cancer cells. Using prostate cancer (PCa) as a model disease, we developed a cell-uptake selection strategy...

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Detalhes bibliográficos
Main Authors: Xiao, Zeyu, Levy-Nissenbaum, Etgar, Alexis, Frank, Lupták, Andrej, Teply, Benjamin A., Chan, Juliana M., Shi, Jinjun, Digga, Elise, Cheng, Judy, Langer, Robert, Farokhzad, Omid C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515647/
https://ncbi.nlm.nih.gov/pubmed/22214176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn204165v
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