Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

Targeted uptake of therapeutic nanoparticles in a cell-, tissue-, or disease-specific manner represents a potentially powerful technology. Using prostate cancer as a model, we report docetaxel (Dtxl)-encapsulated nanoparticles formulated with biocompatible and biodegradable poly(d,l-lactic-co-glycol...

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Bibliografiske detaljer
Main Authors: Farokhzad, Omid C., Cheng, Jianjun, Teply, Benjamin A., Sherifi, Ines, Jon, Sangyong, Kantoff, Philip W., Richie, Jerome P., Langer, Robert
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458875/
https://ncbi.nlm.nih.gov/pubmed/16606824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601755103
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