Plasmodium falciparum Rosetting Epitopes Converge in the SD3-Loop of PfEMP1-DBL1α

The ability of Plasmodium falciparum parasitized RBC (pRBC) to form rosettes with normal RBC is linked to the virulence of the parasite and RBC polymorphisms that weaken rosetting confer protection against severe malaria. The adhesin PfEMP1 mediates the binding and specific antibodies prevent seques...

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Bibliographic Details
Main Authors: Angeletti, Davide, Albrecht, Letusa, Blomqvist, Karin, Quintana, María del Pilar, Akhter, Tahmina, Bächle, Susanna M., Sawyer, Alan, Sandalova, Tatyana, Achour, Adnane, Wahlgren, Mats, Moll, Kirsten
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515580/
https://ncbi.nlm.nih.gov/pubmed/23227205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050758
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