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Elastase and Tryptase Govern TNFα-Mediated Production of Active Chemerin by Adipocytes
Chemerin is a leukocyte chemoattractant and adipokine with important immune and metabolic roles. Chemerin, secreted in an inactive form prochemerin, undergoes C-terminal proteolytic cleavage to generate active chemerin, a ligand for the chemokine-like receptor-1 (CMKLR1). We previously identified th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3515524/ https://ncbi.nlm.nih.gov/pubmed/23227233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051072 |
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