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The Role of the 3′UTR Region in the Regulation of the ACVR1/Alk-2 Gene Expression

BACKGROUND: The ACVR1/Alk-2 gene, encoding a BMP type I receptor, is mutated in Fibrodysplasia Ossificans Progressiva, a severe form of heterotopic ossification. Regulation of ACVR1/Alk-2 expression, still poorly understood, is likely to be controlled by transcriptional and post-transcriptional mech...

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Hlavní autoři: Mura, Marzia, Cappato, Serena, Giacopelli, Francesca, Ravazzolo, Roberto, Bocciardi, Renata
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515447/
https://ncbi.nlm.nih.gov/pubmed/23227223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050958
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