Pathogenesis of a Pichinde Virus Strain Adapted to Produce Lethal Infections in Guinea Pigs

A model for studying the pathogenesis of virulent arenavirus infection was developed by adapting Pichinde virus to produce lethal infections of inbred guinea pigs. This adapted Pichinde virus retained low virulence for primates, thus potentially reducing the biohazard to investigators. Whereas all i...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Jahrling, P. B., Hesse, R. A., Rhoderick, J. B., Elwell, M. A., Moe, J. B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1981
Schlagworte:	Viral Infections and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6265367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.32.2.872-880.1981
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