Pathogenesis of a Pichinde Virus Strain Adapted to Produce Lethal Infections in Guinea Pigs

A model for studying the pathogenesis of virulent arenavirus infection was developed by adapting Pichinde virus to produce lethal infections of inbred guinea pigs. This adapted Pichinde virus retained low virulence for primates, thus potentially reducing the biohazard to investigators. Whereas all i...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Jahrling, P. B., Hesse, R. A., Rhoderick, J. B., Elwell, M. A., Moe, J. B.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1981
Assuntos:	Viral Infections and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6265367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.32.2.872-880.1981
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