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Evaluation of A/Alaska/6/77 (H3N2) cold-adapted recombinant viruses derived from A/Ann Arbor/6/60 cold-adapted donor virus in adult seronegative volunteers.

The influenza A/Ann Arbor/6/60 (H2N2) cold-adapted (ca) virus was evaluated as a donor of attenuating genes to new variants of influenza A virus. This ca donor virus was mated with the A/Alaska/6/77 (H3N2) wild-type virus, and three A/Alaska/6/77 (H3N2) ca recombinant viruses were produced. The pare...

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Bibliographic Details
Main Authors: Murphy, B R, Chanock, R M, Clements, M L, Anthony, W C, Sear, A J, Cisneros, L A, Rennels, M B, Miller, E H, Black, R E, Levine, M M, Betts, R F, Douglas, R G, Maassab, H F, Cox, N J, Kendal, A P
Format: Artigo
Language:Inglês
Published: 1981
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC351503/
https://ncbi.nlm.nih.gov/pubmed/7251144
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