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Preferential binding of K(+) ions in the selectivity filter at equilibrium explains high selectivity of K(+) channels

K(+) channels exhibit strong selectivity for K(+) ions over Na(+) ions based on electrophysiology experiments that measure ions competing for passage through the channel. During this conduction process, multiple ions interact within the region of the channel called the selectivity filter. Ion select...

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Autori principali: Liu, Shian, Bian, Xuelin, Lockless, Steve W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514730/
https://ncbi.nlm.nih.gov/pubmed/23148260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210855
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