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ADAR1 ablation decreases bone mass by impairing osteoblast function in mice
Bone mass is controlled through a delicate balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption. We show here that RNA editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) is critical for proper control of bone mass. Postnatal conditional knockout of Adar1...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514579/ https://ncbi.nlm.nih.gov/pubmed/23123729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2012.10.068 |
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