ADAR1 ablation decreases bone mass by impairing osteoblast function in mice

Bone mass is controlled through a delicate balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption. We show here that RNA editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) is critical for proper control of bone mass. Postnatal conditional knockout of Adar1...

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Detalhes bibliográficos
Main Authors: Yu, Shibing, Sharma, Rohit, Nie, Daibang, Jiao, Hongli, Im, Hee-Jeong, Lai, Yumei, Zhao, Zhongfong, Zhu, Ke, Fan, Jie, Chen, Di, Wang, Qingde, Xiao, Guozhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514579/
https://ncbi.nlm.nih.gov/pubmed/23123729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2012.10.068
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