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Humanized mice as a preclinical tool for infectious disease and biomedical research

Immunodeficient mice bearing an IL2rγ(null) gene permit engraftment of a functional human immune system and study of human-specific infectious agents that was not previously possible.

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Autori principali: Shultz, Leonard D., Brehm, Michael A., Bavari, Sina, Greiner, Dale L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514446/
https://ncbi.nlm.nih.gov/pubmed/22211979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2011.06310.x
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