Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins

BACKGROUND: Methionine (Met) residues in proteins can be readily oxidized by reactive oxygen species to Met sulfoxide (MetO). MetO is a promising physiological marker of oxidative stress and its inefficient repair by MetO reductases (Msrs) has been linked to neurodegeneration and aging. Conventional...

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Autors principals: Liang, Xinwen, Kaya, Alaattin, Zhang, Yan, Le, Dung Tien, Hua, Deame, Gladyshev, Vadim N
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514235/
https://ncbi.nlm.nih.gov/pubmed/23088625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-13-21
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