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Analysis of Methionine/Selenomethionine Oxidation and Methionine Sulfoxide Reductase Function Using Methionine-Rich Proteins and Antibodies against Their Oxidized Forms

Methionine (Met) residues are present in most proteins. However, this sulfur-containing amino acid is highly susceptible to oxidation. In cells, the resulting Met sulfoxides are reduced back to Met by stereospecific reductases MsrA and MsrB. Reversible Met oxidation occurs even in the absence of str...

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Detalhes bibliográficos
Main Authors: Le, Dung Tien, Liang, Xinwen, Fomenko, Dmitri E., Raza, Ashraf S., Chong, Chom-Kyu, Carlson, Bradley A., Hatfield, Dolph L., Gladyshev, Vadim N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844923/
https://ncbi.nlm.nih.gov/pubmed/18505275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800422s
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