Eculizumab in paroxysmal nocturnal hemoglobinuria with Budd-Chiari syndrome progressing despite anticoagulation

Paroxysmal nocturnal hemoglobinuria (PNH) is a progressive, life-threatening disorder characterized by chronic intravascular hemolysis caused by uncontrolled complement activation. Hepatic vein thrombosis (Budd-Chiari syndrome) is common in PNH patients. This case report describes the response to ec...

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Detalhes bibliográficos
Main Authors: Brodsky, Andrés, Mazzocchi, Octavio, Sánchez, Fabiana, Khursigara, Gus, Malhotra, Suneil, Volpacchio, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514094/
https://ncbi.nlm.nih.gov/pubmed/23210433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2162-3619-1-26
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