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Mena binds α5 integrin directly and modulates α5β1 function

Mena is an Ena/VASP family actin regulator with roles in cell migration, chemotaxis, cell–cell adhesion, tumor cell invasion, and metastasis. Although enriched in focal adhesions, Mena has no established function within these structures. We find that Mena forms an adhesion-regulated complex with α5β...

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Detalhes bibliográficos
Main Authors: Gupton, Stephanie L., Riquelme, Daisy, Hughes-Alford, Shannon K., Tadros, Jenny, Rudina, Shireen S., O.Hynes, Richard, Lauffenburger, Douglas, Gertler, Frank B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514034/
https://ncbi.nlm.nih.gov/pubmed/22908313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202079
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