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Wnt-11 and Fz7 reduce cell adhesion in convergent extension by sequestration of PAPC and C-cadherin

Wnt-11/planar cell polarity signaling polarizes mesodermal cells undergoing convergent extension during Xenopus laevis gastrulation. These shape changes associated with lateral intercalation behavior require a dynamic modulation of cell adhesion. In this paper, we report that Wnt-11/frizzled-7 (Fz7)...

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Main Authors: Kraft, Bianca, Berger, Corinna D., Wallkamm, Veronika, Steinbeisser, Herbert, Wedlich, Doris
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514027/
https://ncbi.nlm.nih.gov/pubmed/22908314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110076
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